Microwave Irradiation Effect on Intermolecular and Intramolecular Friedel-Crafts Acylation Reaction

Biocatalytic Friedel–Crafts Acylation and Fries Reaction

The Friedel-Crafts acylation is commonly used for the synthesis of aryl ketones, and a biocatalytic version, which may benefit from the chemo- and regioselectivity of enzymes, has not yet been introduced. Described here is a bacterial acyltransferase which can catalyze Friedel-Crafts C-acylation of phenolic substrates in buffer without the need of CoA-activated reagents. Conversions reach up to...

Intramolecular Friedel–Crafts acylation of acyclic (h-diene)Fe(CO)3 complexes

Intramolecular cyclization of (h-diene)Fe(CO)3 complexes bearing a carboxylic acid chloride functionality at the terminal side chain of the diene ligand produces (s, h-allyl)Fe(CO)3 complexes, whereas treatment of the acid chloride complexes with Et3N and AlCl3 provides (h-diene)Fe(CO)3 complexes containing a cyclopentanone moiety. © 2000 Elsevier Science S.A. All rights reserved.

Mild and Nondestructive Chemical Modification of Carbon Nanotubes (CNTs): Direct Friedel-Crafts Acylation Reaction

Friedel–Crafts acylation of 2-methoxynaphthalene over zeolite catalysts

The Friedel–Crafts acylation of 2-methoxynaphthalene was carried out in the liquid-phase batch conditions using Hmordenite, H-beta and H-Y zeolite as catalysts. All the catalysts showed 35–40% conversion in the temperature range of 100–150◦C. 1-Acyl-2-methoxynaphthalene was formed as the primary product. When acetyl chloride was used as the acylating agent, a higher yield of 6-acyl-2-methoxynap...

Deciphering DNA-based asymmetric catalysis through intramolecular Friedel-Crafts alkylations.

We describe asymmetric intramolecular Friedel-Crafts alkylations with a DNA-based hybrid catalyst and propose a plausible binding model. This study shows promise for studying relationships between the helical chirality of DNA and enantioselectivity of the chemical reaction.